Pharmaniaga Bupivacaine 0.5%

Pharmaniaga Bupivacaine 0.5%

bupivacaine

Manufacturer:

Pharmaniaga Manufacturing Berhad

Distributor:

Pharmaniaga Logistics
Concise Prescribing Info
Contents
Bupivacaine HCl
Indications/Uses
Local or regional anaesth & analgesia.
Dosage/Direction for Use
Individualized dosage. Max: 2 mg/kg.
Contraindications
Hypersensitivity to bupivacaine or amide-type local anaesth. Patients w/ uncorrected hypotension & complete heart block. Not to be inj into inflamed or infected tissues nor applied to damaged skin &/or in the presence of septicaemia; not to be applied to the middle ear. Obstet paracervical block, IV regional anaesth (Bier's block) & all IV infusion. Lactation.
Special Precautions
Insert IV cannula prior to local anaesth inj. Constant monitoring of CV & resp vital signs & patient's state of consciousness after each inj. Major peripheral nerve block. Patients w/ epilepsy, impaired cardiac conduction, bradycardia, severe shock or digitalis intoxication; impaired CV function; Stokes-Adams syndrome or Wolff-Parkinson-White syndrome; preexisting neurological or neuromuscular disease (eg, myasthenia gravis); serious CNS or spinal cord diseases (eg, meningitis, spinal fluid block, cranial or spinal haemorrhage, tumours, poliomyelitis, syphilis, TB or metastatic spinal cord lesions); hyperthyroidism; hypersensitivity. Patients being treated w/ anti-arrhythmic class III drugs (eg, amiodarone). Inadvertent intravascular or subarachnoid inj; post-op IA continuous infusion. May impair ability to drive or operate machinery. Advanced hepatic disease or severe renal/hepatic impairment. Pregnancy. Childn <12 yr. Elderly, debilitated patients, including those w/ partial or complete conduction block.
Adverse Reactions
Lightheadedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred vision, diplopia, nausea, vomiting, sensations of heat, cold or numbness, urinary retention, paraesthesia circumoral, paraesthesia, hyperacusis, twitching, tremors, convulsions, unconsciousness, resp depression &/or arrest, agitation, tongue numbness, difficulty swallowing & slurred speech; bradycardia, hypotension & CV collapse which may lead to cardiac arrest; maternal hypotension; spinal block of varying magnitude (including total spinal block), hypotension secondary to spinal block, loss of bladder, bowel control, perineal sensation & sexual function; backache & headache; cutaneous lesions, urticaria, oedema or anaphylactoid reactions; joint pain, stiffness & loss of motion.
Drug Interactions
Potentiation of cardiac effects w/ amide-type local anaesth eg, mexiletine & lignocaine. Caution w/ anti-arrythmic class III drugs eg, amiodarone.
ATC Classification
N01BB01 - bupivacaine ; Belongs to the class of amides. Used as local anesthetics.
Presentation/Packing
Form
Pharmaniaga Bupivacaine 0.5% soln for inj 100 mg/20 mL
Packing/Price
20 mL x 5 × 1's
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