In conjunction w/ other anti-TB drugs in the treatment of all forms of TB.
Dosage/Direction for Use
Adult & adolescent Prophylaxis: 300 mg once daily. Treatment: 300 mg once daily or initially 300 mg once daily for 2 mth then 15 mg/kg bd wkly for the remainder of the therapy. Max: 900 mg. Childn Prophylaxis: 10 mg/kg. Treatment: 10-20 mg/kg. Max: 300 mg once daily.
Hypersensitivity to INH, ethionamide, pyrazinamide, niacin (nicotinic acid) or other chemically related medications. Epileptics & patients w/ chronic alcoholism. Patients taking potentially hepatotoxic agents. Hepatic or renal impairment.