Adult patients: One capsule daily. An increase in daily dosage to 2 capsules daily did not evidence any increase in efficacy. The usual treatment duration is between 3 and 6 months. At the end of this treatment duration, the practitioner may consider the need for a new course if required. No special action is needed if one or more dose(s) are missed.
Paediatric population: The safety and efficacy of PIASCLEDINE capsule in children has not been established, while there is no relevant use of PIASCLEDINE capsule in the paediatric population. Therefore PIASCLEDINE is not to be used in children and adolescents below the age of 18.
Other special populations: Elderly patients: There was no specific clinical study of PIASCLEDINE in elderly patient population. However, the overall clinical experience with PIASCLEDINE was observed in patient population with an actual mean age around 60 years old, with a significant proportion of patients over 65 years old. Therefore, no dosage adjustment is to be made in elderly, otherwise healthy, patients.
Method of administration: Oral use. Capsule is to be swallowed as a whole, without chewing, with a glass of water, generally in the middle of a meal.