Plazilin

Plazilin

metoclopramide

Manufacturer:

Gland Pharma

Distributor:

Unimed
Concise Prescribing Info
Contents
Metoclopramide
Indications/Uses
Nausea & vomiting induced by gastroduodenal disorders ie, flatulent dyspepsia, gastritis, gastroenteritis, duodenal ulcer & hiatus hernia, hepatobiliary disorders ie, uremia, cardiac disease, radiation therapy & migraine, drugs ie, digitalis, metronidazole, pethidine, morphine, cancer chemotherapy.
Dosage/Direction for Use
Adult 1 IM inj 1-3 times daily or 1 IV inj when required. Childn 0.5 mg/kg daily in 3-4 divided doses. Pre-/post-op nausea & vomiting & control of analgesic-induced vomiting 1 IM inj. Mendelson's syndrome 1 IM/IV inj 1-1½ hr prior to anesth induction. Radiology 1-2 IM inj 10-15 min or 1-2 IV inj 5-10 min before barium meal. Diagnostic gastroenterology procedure 1-2 IM inj 10-15 min before procedure.
Contraindications
Hypersensitivity. Presence of GI haemorrhage, mechanical obstruction or perforation, immediate use after GI surgery, patients w/ epilepsy or extrapyramidal syndrome; phaeochromocytoma; breast carcinoma.
Special Precautions
Avoid dilution or rapid inj. Large doses. Avoid use during 1st trimester of pregnancy. Lactation.
Adverse Reactions
Restlessness, drowsiness, fatigue, lassitude, extrapyramidal effects, tardive dyskinesia, Parkinsonian-like symptoms, akathisia, galactorrhoea, gynaecomastia.
Drug Interactions
Antagonized GI effects by anticholinergics & narcotic analgesics. Additive sedative effects w/ alcohol, sedatives, hypnotics, narcotics, tranquilizers. Released catecholamines w/ MAOIs. Diminished absorption of digoxin. Increased absorption of acetaminophen, tetracycline, l-dopa, ethanol, cyclosporine. Influenced rate of insulin absorption.
MIMS Class
Antiemetics
ATC Classification
A03FA01 - metoclopramide ; Belongs to the class of propulsives. Used in the treatment of functional gastrointestinal disorders.
Presentation/Packing
Form
Plazilin inj 5mg/mL
Packing/Price
2 mL x 10 × 1's
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