Policresulen


Generic Medicine Info
Indications and Dosage
Vaginal
Cervicitis, Vaginitis
Adult: As supp: Insert 1 supp deep into vagina every other day at bedtime. Treatment duration depends on severity of condition.
Special Precautions
Pregnancy and lactation. 
Adverse Reactions
Significant: Local irritation.
Reproductive system and breast disorders: Vaginal dryness, vaginal discharge.
Patient Counseling Information
Avoid sexual intercourse during and 7 days after treatment. Avoid use of irritant soap during treatment. Not recommended for use during menstruation.
Action
Description: Policresulen is an organic acid with a topical healing effect. It promotes haemostasis by enabling blood protein coagulation and allowing contraction of muscle fibres of small calibre blood vessels, and chemical debridement through interaction with devitalised plasma membrane phospholipid molecules, thus causing denaturation of cellular proteins allowing for their removal. Its acidity and coagulating properties provide antimicrobial effects against staphylococcus spp, streptococcus spp, and Candida albicans.
Synonym: Metacresolsuphonic acid-formaldehyde
Pharmacokinetics:
Excretion: Elimination half-life: 4-5 hours.
Chemical Structure

Chemical Structure Image
Policresulen

Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 3050404, Policresulen. https://pubchem.ncbi.nlm.nih.gov/compound/Policresulen. Accessed Apr. 27, 2021.

Storage
Store below 25°C. Protect from light.
ATC Classification
G01AX03 - policresulen ; Belongs to the class of other antiinfectives and antiseptics. Used in the treatment of gynecological infections.
D08AE02 - policresulen ; Belongs to the class of phenol and derivatives antiseptics. Used in the treatment of dermatological diseases.
References
Anon. Policresulen. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 13/04/2021.

Buckingham R (ed). Policresulen. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 13/04/2021.

Disclaimer: This information is independently developed by MIMS based on Policresulen from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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