Concise Prescribing Info
Dosage/Direction for Use
Adult : Vaginal As pessary: Insert 6.5 mg once daily at bedtime.
Dosage Details
Adult: As pessary: Insert 6.5 mg once daily at bedtime.
Undiagnosed abnormal genital bleeding, history of known or suspected breast cancer.
Special Precautions
Patient with known thromboembolic states, undergone hysterectomy.
Adverse Reactions
Significant: Vaginal discharge.
Investigations: Weight fluctuation.
Reproductive system and breast disorders: Abnormal Pap smear, cervical/uterine polyps, breast mass.
Perform breast and pelvic exam. Monitor for excessive bleeding or vaginal discharge.
Description: Prasterone is an inactive endogenous steroid. The exact mechanism of action is not fully established, however, it exhibits both androgenic and oestrogenic activity.
Synonym: dehydroepiandrosterone.
Metabolism: Metabolised via dehydrogenase, reductase, and aromatase to 2 active metabolites (estradiol and testosterone).
Chemical Structure

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Store between 5-30°C. Follow applicable procedures for receiving, handling, administration, and disposal.
ATC Classification
A14AA07 - prasterone ; Belongs to the class of androstan derivative anabolic steroids used as systemic anabolic agents.
Disclaimer: This information is independently developed by MIMS based on Prasterone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by
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