Prelone

Prelone

prednisolone

Manufacturer:

Sunward

Distributor:

Antah Pharma
Concise Prescribing Info
Contents
Prednisolone
Indications/Uses
Primary or secondary adrenocortical insufficiency; rheumatic & hematologic disorders; bronchial asthma; collagen (SLE), dermatologic (pemphigus, severe psoriasis & seborrheic dermatitis), ophth (eye inflammation, herpes zoster ophthalmicus, allergic conjunctivitis), neoplastic (leukemias), GI (ulcerative colitis) diseases; edematous states.
Dosage/Direction for Use
Initially 5-60 mg daily in divided doses, as single or double dose on alternate days depending on disease.
Administration
Should be taken with food.
Contraindications
Hypersensitivity. Systemic fungal infection.
Special Precautions
CHF, DM, HTN, recent intestinal anastomoses, infectious diseases, myasthenia gravis, ocular herpes simplex; scleroderma renal crisis. Closely observe patients w/ quiescent TB. Prolonged use. Avoid abrupt w/drawal. Concomitant use w/ CYP3A inhibitors. Chronic renal failure. Women of childbearing potential. Pregnancy & lactation. Growth & development of infants & childn. Elderly.
Adverse Reactions
Fluid & electrolyte disturbance, muscle weakness, osteoporosis, acute pancreatitis, cushingoid state, growth retardation, menstrual irregularities, increased IOP & intracranial pressure w/ papilledema, visual disturbances, latent DM manifestations, peptic ulcer w/ possible perforation & hemorrhage, wound healing impairment, convulsion.
Drug Interactions
Enhanced metabolism by phenytoin, phenobarb, ephedrine & rifampicin; barbiturates. Increased systemic side effects w/ CYP3A inhibitors eg, cobicistat-containing products.
ATC Classification
H02AB06 - prednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
Prelone syr 3 mg/5 mL
Packing/Price
(raspberry flavour) 100 mL x 1's; (raspberry flavour) 120 mL x 1's; (raspberry flavour) 60 mL x 1's
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