Known or suspected pregnancy (see Pregnancy and Lactation under Use in Pregnancy & Lactation).
Undiagnosed abnormal uterine bleeding.
Known, suspected, or history of breast cancer.
Known or suspected estrogen-dependent neoplasia (e.g., endometrial cancer, endometrial hyperplasia).
Active or history of confirmed arterial thromboembolic disease (e.g., stroke, myocardial infarction) or venous thromboembolism (such as deep venous thrombosis, pulmonary embolism).
Active or chronic liver dysfunction or disease.
Known thrombophilic disorders (e.g., protein C, protein S, or antithrombin deficiency).
Hypersensitivity to any component of this medication.