Known,suspected, or history of breast cancer.
Known or suspected estrogen-dependent neoplasia (e.g., endometrial cancer, endometrial hyperplasia).
Known or suspected pregnancy (see Fertility, Pregnancy and Lactation under Use in Pregnancy & Lactation).
Undiagnosed abnormal uterine bleeding.
Active or history of confirmed arterial thromboembolic disease (e.g., stroke, myocardial infarction) or venous thromboembolism (such as deep venous thrombosis, pulmonary embolism).
Hypersensitivity to any component of this medication.
Active or chronic liver dysfunction or disease.
Known thrombophilic disorders (e.g. protein C, protein S, or antithrombin deficiency).