Proglumetacin


Concise Prescribing Info
Indications/Uses
Pain and inflammation associated with musculoskeletal and joint disorders.
Dosage/Direction for Use
Adult : PO ≤600 mg/day in divided doses.
Dosage Details
Oral
Pain and inflammation associated with musculoskeletal and joint disorders
Adult: Up to 600 mg/day in divided doses.
Administration
Should be taken with food.
Contraindications
Neonates with untreated infection, significant renal impairment or necrotising enterocolitis. Infants who are bleeding, have thrombocytopenia or coagulation defects.
Special Precautions
Caution when used in epilepsy, parkinsonism or psychiatric disorders. Regular blood and ophthalmic examinations are recommended in patients on long-term therapy.
Adverse Reactions
GI disturbances, headache, vertigo, dizziness and lightheadedness.
Drug Interactions
Concurrent use with ACE inhibitors may increase risk of renal impairment and hyperkalaemia. Increased risk of GI bleeding when used with alcohol.
Lab Interference
May cause false-negative results in dexamethasone suppression test.
Action
Description: Proglumetacin, an NSAID, is an indole acetic acid derivative related to indometacin.
Disclaimer: This information is independently developed by MIMS based on Proglumetacin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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