Patient Medicine Information
Why do I need this medicine?
Proguanil is used together with other medicines for the treatment and prevention of malaria.
How do I take this medicine?
Take Proguanil exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take this medicine together with food or immediately after a meal. Try to take it at the same time each day.

If you are taking this medicine for the prevention of malaria, take it 1 week or at least 2 days before travel. Continue taking this medicine on a daily basis throughout the whole period of travel and for at least 4 weeks after leaving the area. If your trip is longer than 28 days, discuss with your doctor how you should take this medicine.

If you have difficulties swallowing tablets, you may crush the tablet and mix it with milk, honey or jam. Stir and drink immediately.

Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.

Do not skip any doses. You must complete the entire course of this medicine. If you don't, the infection will not clear completely.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have severe kidney disease as this medicine may not be suitable for you.
What should I take note of while taking this medicine?
Let your doctor know if you are pregnant or breastfeeding.

In addition to taking Proguanil, you must also take preventive measures to avoid mosquito bites. Use an effective insect repellent, wear long-sleeved shirts and long pants to reduce exposure and avoid going out between dusk to dawn. An effective insect repellent should contain at least 20-33% diethyltoluamide (DEET).

The symptoms of malaria are fever, chills, headache, muscle pain and a flu-like illness. Consult a doctor immediately if you experience these symptoms during your travel or anytime within 1 year after leaving the area, especially within 3 months after your exposure.
What side effects could I experience?
Proguanil may cause any of the following side effects: stomach discomfort, diarrhoea, constipation and mouth sores.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines for blood thinning e.g. warfarin
- medicines for depression e.g. fluvoxamine

Proguanil should not be taken with antacids as antacids could reduce the effectiveness of this medicine. If you must take antacids, take it at least 2-3 hours after you have taken this medicine.

This list does not include all medicines that may interact with Proguanil.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on proguanil-oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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