Prostin VR

Prostin VR

alprostadil

Manufacturer:

Pfizer

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Alprostadil
Indications/Uses
Palliative, not definitive, therapy to temporarily maintain ductus arteriosus patency until corrective or palliative surgery can be performed in neonates who have congenital heart defects & who depend upon patent ductus for survival.
Dosage/Direction for Use
Initially 0.05-0.1 mcg/kg/min by continuous IV infusion.
Special Precautions
Cortical proliferation of long bones. Monitor resp status & arterial pressure throughout treatment. Long-term use. Not be used in neonates w/ resp distress syndrome. Neonates w/ bleeding tendencies.
Adverse Reactions
Apnea, fever, seizures; flushing, bradycardia, hypotension, tachycardia, cardiac arrest, edema; diarrhea; disseminated intravascular coagulation; sepsis, hypokalemia.
MIMS Class
Other Cardiovascular Drugs
ATC Classification
C01EA01 - alprostadil ; Belongs to the class of prostaglandins used in cardiac therapy.
Presentation/Packing
Form
Prostin VR soln for infusion 500 mcg/mL
Packing/Price
1 mL x 5 × 1's
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