Avoid use in patients w/ fluoroquinolone hypersensitivity & known history of myasthenia gravis. History of aneurysm disease, preexisting aortic aneurysm &/or aortic dissection, risk factors or conditions predisposing for aortic aneurysm & dissection (eg, Marfan syndrome, vascular Ehlers-Danlos syndrome, Takayasu arteritis, giant cell arteritis, Behcet's disease, HTN, known atherosclerosis). Increased risk of tendinitis & tendon rupture. Patients w/ solid organ transplants. Sensory or sensorimotor polyneuropathy. Avoid urine alkalinity. Ensure adequate hydration. Concomitant use w/ corticosteroids. May affect ability to drive & use machines. Renal impairment. Avoid use during pregnancy. Not to be used during lactation. Elderly >60 yr.
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