Ramucirumab is used on its own or together with other medicines to treat cancer of the stomach, colon or rectum, and lungs.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
Ramucirumab is to be given intravenously (into the vein). It is delivered directly into the bloodstream via the blood vessel.
Your doctor or nurse will administer the injection for you.
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Ramucirumab.
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
Inform your doctor if you the following conditions:
- heart disease
- liver disease
- kidney disease
- high blood pressure
- bleeding disorder or conditions which increases the risk of bleeding
It is important that you do not get pregnant while being treated with this medicine. You may wish to discuss birth control methods with your doctor or pharmacist. Avoid pregnancy for at least 3 months after you stop taking this medicine.
Let your doctor know if you are breastfeeding.
If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking Ramucirumab as this medicine may increase the risk of problems with wound healing.
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Routine monitoring of your blood pressure, urine protein, liver and thyroid function may be needed while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
Ramucirumab may cause any of the following side effects: headache, tiredness, nose bleed, diarrhoea, and stomach pain.
Some side effects may need immediate medical help. Alert your doctor immediately if you experience any of the following:
- wound healing problems
- bleeding problems e.g. vomiting blood, coughing up blood, black or tarry stools, bleeding gums, unusual and persistent bleeding or bruising
- signs of stroke e.g. sudden numbness or weakness of the arms and legs, slurred speech, sudden blurred vision, confusion, or unsteadiness
- signs of heart attack e.g. chest pain or heaviness of the chest
- signs of hole in the wall of your stomach e.g. severe stomach pain, feeling sick, vomiting, fever or chills
- infusion reactions e.g. fever, chills, rash, difficulty breathing, and swelling of the hands, legs, face or mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in the refrigerator, between 2-8 °C. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used.
Store reconstituted solution between 2-8°C for up to 24 hours.
Do not shake. Protect from light.
Do not use this medicine if it becomes cloudy or if it has changed in colour.
As this is a cancer medicine, always return any unused or expired tablets to the clinic, hospital or pharmacy for disposal. Do not throw it away in the household waste.