The highest documented dose of Ravida was 320 mg once daily for 5 days in healthy volunteers. There were no untoward effects observed at these dose levels and adverse events were similar in frequency and severity to those reported in the placebo groups. The effects of higher doses/exposures are not known.
No specific antidote is available for overdose with ravidasvir. If overdose occurs, the patient must be monitored for evidence of toxicity. Treatment of overdose with Ravida consists of general supportive measures including monitoring of vital signs, as well as observation of the clinical status of the patient.