Anemia w/ CRF
Correction phase: SC inj
Initially 3 x 20 IU/kg wkly, may be increased every 4 wk by 3 x 20 IU/kg wkly if increase is inadequate <0.25 g/dL wkly. Wkly dose can be divided into daily doses. IV inj
Initially 3 x 40 IU/kg wkly, may be increased after 4 wk to 80 IU/kg 3 times wkly. Further increased at 20 IU/kg increments if needed 3 times wkly at mthly intervals. Max dose: Not to exceed 720 IU/kg wkly. Maintenance phase: Initially reduced to ½ of previously administered amount. Adjust dose subsequently at 2-4 wk intervals individually. Prevention of anemia of prematurity SC inj
3 x 250 IU/kg wkly for 6 wk. Symptomatic treatment of anemia in cancer SC inj
Initially 30,000 IU wkly (approx 450 IU/kg wkly based on ave wt) for 4 wk. If Hb value increased by at least 1 g/dL, continue therapy; if not, double wkly dose. After 8 wk therapy, if Hb value has not increased by at least 1 g/dL, discontinue therapy. Continue therapy up to 4 wk after end of chemotherapy. Max: Not to exceed 60,000 IU wkly. SC/IV inj Increasing amount of autologous blood
Individualized dosage administered twice wkly over 4 wk. Max IV Dose: 1,600 IU/kg wkly. Max SC Dose: 1,200 IU/kg wkly.