Repatha Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Storage Patient Counseling Information MIMS Class ATC Classification Presentation/Packing

Concise Prescribing Info

Contents

Evolocumab

Indications/Uses

Adjunct to diet & standard care therapy including moderate- to high-intensity statin therapy alone or in combination w/ other lipid-lowering therapy to reduce risk of MI, stroke & coronary revascularization in adults w/ atherosclerotic CV disease. Reduction of elevated LDL-C in adults w/ primary hyperlipidemia including heterozygous familial hypercholesterolemia (HeFH): Adjunct to diet & statin therapy w/ or w/o other lipid-lowering therapies in patients requiring additional lowering of LDL-C, or alone or in combination w/ non-statin lipid-lowering therapies for patients whom statin is contraindicated. Adjunct to diet & other LDL-lowering therapies in patients w/ HoFH requiring additional lowering of LDL-C.

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Dosage/Direction for Use

SC Established CV disease or primary hyperlipidemia including HeFH 140 mg every 2 wk or 420 mg once mthly. HoFH 420 mg once mthly.

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Contraindications

Hypersensitivity.

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Special Precautions

Discontinue use if hypersensitivity reaction occurs. Severe hepatic impairment. Pregnancy & lactation. Ped patients <13 yr. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Nasopharyngitis, upper resp tract infection, flu, back pain, inj site reactions (including erythema, pain, bruising), allergic reactions (rash, eczema, erythema, urticaria); DM, angioedema, flu-like illness.

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Storage

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Description

View Repatha description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Dyslipidaemic Agents

ATC Classification

C10AX13 - evolocumab ; Belongs to the class of other lipid modifying agents.

Patient Counseling Information

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Presentation/Packing

Form

Repatha soln for inj 140 mg/mL

Packing/Price

((auto-injector)) 1's

Repatha

evolocumab

Manufacturer:

Amgen

Distributor:

Zuellig Pharma