Severe & clinically unstable concomitant disease eg, liver, CV or lung disease, neurological or psychiatric disorders, cancer or AIDS & other endocrine disorders; history of arrhythmias or ischaemic CV disease. Concomitant use of OC. Galactose intolerance, Lapp-lactase deficiency or glucose-galactose malabsorption. May affect ability to drive or operate machinery. Severe renal & hepatic impairment. Pregnancy & lactation. Childn, adolescent <18 yr.