Retafyllin CR Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Theophylline

Indications/Uses

Symptomatic relief & prevention of asthma & reversible bronchospasm associated w/ chronic bronchitis & emphysema.

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Dosage/Direction for Use

Adult 400-600 mg as single dose in the evening or 200-300 mg 12 hrly. Childn >30 kg 200 mg bd, 20-30 kg 150 mg bd, 12-20 kg 100 mg bd. Patient not previously treated ½ of maintenance dose for 1st 4-7 days.

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Overdosage

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Administration

May be taken with or without food: May be taken w/ meals to reduce GI discomfort. Swallow whole, do not chew/crush. Tab may be cut into half.

Contraindications

Hypersensitivity. Active PUD.

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Special Precautions

CHF, severe HTN or hypoxemia, hyperthyroidism, viral infections. Smokers. Hepatic disease. Pregnancy & lactation. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

GI disturbances (nausea, vomiting, anorexia, diarrhea, gastric pain), palpitations, cardiac arrhythmias, CNS stimulation.

Drug Interactions

Increased plasma conc w/ cimetidine, ciprofloxacin, erythromycin, troleandomycin, oestrogen, allopurinol, propranolol. Reduced serum conc w/ phenytoin, phenobarb, rifampicin. Decreased plasma conc of lithium. Potentiated hypokalemia caused by β₂-sympathomimetics, steroids, diuretics. Reduced threshold value for inducing convulsions w/ ketamine.

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Storage

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Description

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Action

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MIMS Class

Antiasthmatic & COPD Preparations

ATC Classification

R03DA04 - theophylline ; Belongs to the class of xanthines. Used in the systemic treatment of obstructive airway diseases.

Regulatory Classification

Presentation/Packing

Form

Retafyllin CR tab 200 mg

Packing/Price

100's

Retafyllin CR

theophylline

Manufacturer:

Orion Pharma

Distributor:

Apex