Riboflavin


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Prophylaxis of riboflavin deficiency 1-2 mg/day. Riboflavin deficiency ≤30 mg/day in divided doses. Microcytic anaemia associated w/ splenomegaly and glutathione reductase deficiency 10 mg/day for 10 days.
Dosage Details
Oral
Prophylaxis of riboflavin deficiency
Adult: 1-2 mg daily.

Oral
Riboflavin deficiency
Adult: Up to 30 mg daily in divided doses.
Child: 3-10 mg daily.

Oral
Microcytic anaemia
Adult: Associated with splenomegaly and glutathione reductase deficiency: 10 mg daily for 10 days.
Administration
Should be taken with food.
Incompatibility
Incompatible with alkaline solutions and with tetracycline, erythromycin and streptomycin.
Adverse Reactions
Bright yellow disclouration of urine.
PO: A (Pregnancy Category C if dose is greater than the RDA.)
Drug Interactions
Rate and extent of absorption may be affected by propantheline bromide.
Food Interaction
Extent of absorption increases with food.
Lab Interference
May interfere with certain laboratory tests eg, spectrometry and flourometry test results.
Action
Description: Riboflavin (vitamin B2) is required for energy utilisation from food. It is essential for normal tissue respiration. It is also necessary for the activation of pyridoxine and conversion of tryptophan to nicotinic acid.
Pharmacokinetics:
Absorption: Readily absorbed from the upper GI tract.
Distribution: Widely distributed, including erythrocytes and liver. Crosses the placenta and enters breast milk.
Excretion: About 9% excreted in urine as unchanged drug.
Storage
Store at 15-30°C.
Disclaimer: This information is independently developed by MIMS based on Riboflavin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
  • CCM Riboflavine
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