Ritalin

Ritalin

methylphenidate

Manufacturer:

Novartis

Distributor:

DKSH
Concise Prescribing Info
Contents
Methylphenidate HCl
Indications/Uses
Dosage/Direction for Use
Adult Narcolepsy 20-30 mg daily. Max: 60 mg daily. Childn ≥6 yr ADHD Initially 5 mg once or bd w/ 5-10 mg gradual wkly increments. Max: 60 mg daily.
Administration
May be taken with or without food: Take consistently either always w/ or always w/o food.
Contraindications
Hypersensitivity. Anxiety, tension, agitation, hyperthyroidism, preexisting CV disorder including severe HTN, angina, arterial occlusive disease, heart failure, congenital heart disease, cardiomyopathy, MI, arrhythmia & channelopathies; glaucoma, phaeochromocytoma. Family history of Tourette's syndrome. Concomitant use w/ MAOIs or w/in min of 2 wk discontinuation.
Special Precautions
Not to be used in patients w/ structural cardiac abnormalities or other serious cardiac disorders; preexisting cerebrovascular abnormalities. Not to be initiated in patients w/ acute psychosis, mania or suicidality; emergent psychiatric symptoms (eg, hallucinations or mania, aggressive behaviour & suicidal tendency) or exacerbation of preexisting symptoms. Preexisting CV disorders, family history of sudden death & ventricular arrhythmia; HTN; psychiatric disorders. Epilepsy; priapism; emotionally unstable patients. Marked tolerance & psychological dependence. Avoid abrupt w/drawal. Periodic haemotological monitoring during prolonged therapy. Monitor for suicidal thoughts & unusual changed behaviour. Assess family history & clinical evaluation for Tourette's syndrome. Regularly monitor for emergence or worsening of tics & growth development during treatment. Not recommended to be used w/ serotonergic drugs. May affect ability to drive & use machines. Not recommended during pregnancy. Avoid use during lactation. Not recommended in childn <6 yr.
Adverse Reactions
Nasopharyngitis, decreased appetite, nervousness, insomnia, nausea, dry mouth. Anxiety, restlessness, sleep disorder, agitation, depression, agression, bruxism, tremor, dyskinesia, headache, drowsiness, dizziness, tachycardia, palpitation, arrhythmias, BP & heart rate changes, cough, abdominal pain, vomiting, dyspepsia, toothache, rash, pruritus, urticaria, fever, scalp hair loss, hyperhidrosis, arthralgia, Raynaud's phenomenon, peripheral coldness.
Drug Interactions
Decreased effectiveness of antihypertensives. Possible hypertensive crisis w/ MAOIs. Enhanced adverse CNS effects w/ alcohol. Increased BP w/ anesth during surgery. Risk of serotonin syndrome w/ serotonergic drugs. Drugs elevating BP, coumarin anticoagulants, anticonvulsants, centrally-acting α2-agonists (eg, clonidine), direct & indirect dopaminergic drugs (eg, TCAs, DOPA, antipsychotics), phenylbutazone. Induced false +ve laboratory tests for amphetamines.
ATC Classification
N06BA04 - methylphenidate ; Belongs to the class of centrally-acting sympathomimetics. Used as CNS stimulant.
Presentation/Packing
Form
Ritalin tab 10 mg
Packing/Price
200's
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