Roflumilast is used on its own or together with other medicines to treat severe chronic obstructive pulmonary disease or COPD (a lung disease that causes difficulty in breathing) in patients with chronic bronchitis and history of worsening of COPD symptoms.
Take Roflumilast exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
You may take this medicine with or without food. Try to take it at the same time each day.
It may be necessary for you to take Roflumilast for a long time, such as for a few years. Your doctor will advise you on the treatment timeframe.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Alert your doctor if you have liver disease as Roflumilast may not be suitable for you.
Inform your doctor if you have the following conditions:
- history of depression associated with suicidal thoughts and behaviour
- heart disease
- severe infection
- severe immune system disorder
- low body weight
Let your doctor know if you are pregnant or breastfeeding.
Roflumilast helps control COPD but is not meant to be used if you suddenly feel is it difficult to breathe. This medicine will not help you in this situation. Your doctor may give you another medicine to be available to you at all times for this problem.
For as long as you are taking Roflumilast, you may need to have regular monitoring of your body weight and liver function to check your body’s response to this medicine. Your doctor will advise you how often you need to have them.
Roflumilast may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.
Other side effects include any of the following: headache, difficulty in sleeping, nervousness, depressed mood, nausea, diarrhoea, stomach pain, appetite loss, back pain and weight loss.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- serious weight loss
- thoughts of self-harm
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor or pharmacist if you are taking any of these medicines:
- certain antibiotics e.g. enoxacin, erythromycin
- birth control pills e.g. gestodene, ethinylestradiol
- medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenobarbital, phenytoin
- medicines for tuberculosis or TB e.g. rifampicin
- stomach medicine e.g. cimetidine
- medicine for mood disorders e.g. fluvoxamine
- medicine for fungal infection e.g. ketoconazole
This list does not include all medicines that may interact with Roflumilast.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.