Safrosyn S

Safrosyn S



Pharmaniaga Manufacturing Berhad


Pharmaniaga Logistics
Concise Prescribing Info
Naproxen Na
Musculoskeletal & joint disorders eg, ankylosing spondylitis, OA & RA. Mild to moderate pain eg, dysmenorrhoea. Relief of acute migraine attack. Acute gout.
Dosage/Direction for Use
Musculoskeletal & joint disorders eg, alkylosing spondylitis, OA & RA 275 mg bd or 275 mg in the morning & 550 mg in the evening. Mild to moderate pain eg, dysmenorrhoea 550 mg followed by 275 mg every 6-8 hr. Max dose: 1,375 mg daily. Relief of acute migraine attack 825 mg at 1st attack, then 275 or 550 mg at least ½ hr after initial dose. Max dose: 1,375 mg daily. Acute gout Initially 825 mg followed by 550 mg after 8 hr, then 275 mg 8 hrly.
Should be taken with food.
Active peptic ulceration.
Special Precautions
History of GI haemorrhage of ulcer, cardiac failure or peptic ulceration, SLE, asthma or bronchospasm, bleeding disorders, CV disease, fluid retention. Renal or hepatic impairment; cirrhosis. Pregnancy & lactation. Childn <16 yr. Elderly.
Adverse Reactions
GI disturbances, headache, dizziness, nervousness, tinnitus, depression, drowsiness, insomnia, hypersensitivity reactions, cystitis, haematuria, acute renal failure, interstitial nephritis, nephritic syndrome, anaemia, thrombocytopenia, neutropenia, eosinophilia, agranulocytosis, liver function test abnormalities.
Drug Interactions
Probenecid, lithium, methotrexate, antihypertensives, diuretics, cyclosporin.
MIMS Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
ATC Classification
M01AE02 - naproxen ; Belongs to the class of propionic acid derivatives of non-steroidal antiinflammatory and antirheumatic products.
Safrosyn S tab 275 mg
50 × 10's
Safrosyn S tab 550 mg
50 × 10's
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