Salicylamide


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Pain and fever 325-650 mg 3-4 times/day. Topical Pain and inflammation associated with musculoskeletal and joint disorders As rubefacient preparation: Up to 5%. Apply as directed.
Dosage Details
Oral
Pain and fever
Adult: 325-650 mg 3-4 times daily.

Topical/Cutaneous
Pain and inflammation associated with musculoskeletal and joint disorders
Adult: As rubefacient preparations: Up to 5% to be applied as directed.
Contraindications
Severe renal or hepatic impairment.
Special Precautions
Pregnancy and lactation. Dyspepsia, uncontrolled hypertension, G6PD deficiency and children .
Adverse Reactions
CNS disturbances, GI disturbances, flushing, hyperventilation, sweating, dry mouth, rash and thrombocytopenic purpura. Tinnitus, ecchymosis, haemorrhagic lesions, leukopenia or thrombocytopenia in high doses.
Drug Interactions
Serum levels may be reduced when used with corticosteroids. Increased risk of adverse effects when used with other NSAIDs.
Lab Interference
May interfere with thyroid function tests.
Action
Description: Salicylamide is a salicylic acid derivative but it is not hydrolysed to salicylate. Salicylate-like analgesic and antipyretic effects are inconsistent due to rapid and extensive metabolism during absorption. It may also produce hypotensive effects, through dilation of peripheral blood vessels, and CNS depression.
Pharmacokinetics:
Metabolism: Almost completely metabolised to inactive metabolites during absoption and first pass through the liver.
Disclaimer: This information is independently developed by MIMS based on Salicylamide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in