Shinoxol

Shinoxol

ambroxol

Manufacturer:

Y.S.P. Industries

Distributor:

Y.S.P. Industries
Full Prescribing Info
Contents
Ambroxol hydrochloride.
Description
Each tablet contains Ambroxol Hydrochloride 30 mg.
Ambroxol, a metabolite of bromhexine, is a mucolytic agent capable of increasing sputum volume and reducing its viscosity, improving breathing and reducing cough with no influence on gastric acid sceretion.
Action
Pharmacology: Shinoxol Tablet is a "mucus-modifier". Its active compound is Ambroxol. Several human studies showed that Ambroxol affects the secretomotor activity of serous glands, facilitates the repair of bronchial epithelium, and accelerates mucociliary transport and clearance.
Ambroxol, a metabolite of Bromhexine, has been found to stimulate the synthesis of lung surfactant, as the surfactant may play a role in airway mucus transport acting as a lubricant.
In several studies, Ambroxol also produced statistically significant symptomatic improvement, measured as difficulty in expectoration, coughing, presence of dyspnea and the auscultatory sign as compared to controls.
Absorption after oral administration of Ambroxol was found to be fast and complete. Elimination half-life in the blood was estimated as 20-25 hours in man. In man and rabbit, radioactive-labelled substance was excreted almost completely into the urine.
Indications/Uses
Mucolytic agent used in the treatment of respiratory tract disorders associated with viscid mucus.
Dosage/Direction for Use
For adults: 1 tablet, thrice daily.
For long-term treatment: 1 tablet, twice daily.
To be taken with water after meals.
Overdosage
Symptoms and Treatment for Overdosage, and Antidote(s): There is no specific antidote for its overdosage, therefore, management of the patients should consist of symptomatic and supportive therapy.
Contraindications
It is contraindicated in patients who have shown hypersensitivity to this drug.
Special Precautions
The benefits of the drug in pregnant women during first trimester should be weighed against a possible risk to the fetus.
Side Effects
The side effects of Ambroxol include gastric discomfort, gastralgia, diarrhea, nausea, vomiting, constipation and dyspepsia. Other side effects such as skin rash, pruritis and erythema have also been reported.
Storage
Keep in a tight container. Store at temperature below 30°C. Protect from light and moisture.
Shelf-Life: 3 years from the date of manufacture.
ATC Classification
R05CB06 - ambroxol ; Belongs to the class of mucolytics. Used in the treatment of wet cough.
Presentation/Packing
Tab 30 mg x 10 x 10's, 50 x 10's.
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