Skinoren should be applied to the affected areas of skin twice a day (morning and evening) and rubbed gently into the skin.
Before Skinoren cream is applied, the skin should be thoroughly cleaned with clear water, or if applicable, a mild skin-cleansing agent.
It is important to continue to use Skinoren regularly over the entire period of treatment.
The duration of use of Skinoren can vary from patient to patient and also depends on the severity of the acne. In patients with acne, in general, a distinct improvement becomes apparent after about 4 weeks. To obtain the best results, however, Skinoren should be used regularly over several months. However, Skinoren should not be used continuously for more than 12 months at any time.
The amount of Skinoren to be applied will depend on the size of the affected area. As a guide, a daily dose of approximately 2.5cm/1inch of cream is sufficient for the entire facial area. Excessive amounts of cream must be avoided.
In the event of excessive irritation of the skin (see "Adverse Reactions"), the amount of cream per application should be reduced or the frequency of use of Skinoren should be reduced to once a day until the irritation ceases, or the treatment should be temporarily interrupted for a few days.