The following adverse reactions have been reported after use of benzydamine hydrochloride.
Local Adverse Reactions: The most commonly reported reaction is oral numbness with occasional burning or stinging sensation. Other local adverse effects were less common and included dryness or thirst, tingling, warm feeling in mouth and altered sense of taste.
Systemic Adverse Reactions: These were very uncommon and never of a serious nature. They consisted mainly of nausea, vomiting, retching, gastro-intestinal disorders, dizziness, headache and drowsiness.
Hypersensitivity reactions occur very rarely but may be associated with pruritis, rash, urticaria, photo dermatitis and occasionally laryngospasm.