Sodium stibogluconate - Intralesional

Patient Medicine Information
Why do I need this medicine?
Sodium stibogluconate is used to treat cutaneous leishmaniasis (parasitic skin disease spread by bites of infected sand flies).
How do I use this medicine?
Sodium stibogluconate injection is to be given intralesionally (into the wound). It is injected directly into the affected part of the skin.

Your doctor or nurse will administer the injection for you.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on your condition.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Sodium stibogluconate.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
When should I not use this medicine?
Alert your doctor if you have kidney disease as this medicine may not be suitable for you.

DO NOT use Sodium stibogluconate with amphotericin B or medicines that may cause heart rhythm problems (e.g. astemizole, cisapride, and terfenadine).
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:
  • liver disease
  • heart disease e.g. heart rhythm disorder
Let your doctor know if you are pregnant or breastfeeding.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • Heart rhythm monitoring may be done before and during your treatment.
  • Your doctor may also need to do some routine tests (complete blood count, liver and kidney function tests). Your doctor will advise you on how often you need to have these tests.
What side effects could I experience?
Sodium stibogluconate may cause any of the following side effects: nausea, vomiting, diarrhoea, stomach pain, headache, lack of appetite, joint or muscle pain, tiredness, and lack of energy.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • irregular heartbeat
  • signs and symptoms of pneumonia e.g. cough, difficulty breathing, chest pain when you breathe or cough, fever
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Do not use Sodium stibogluconate with the following medicines:
  • amphotericin B (medicine used to treat fungal infections)
  • medicines used to treat allergy e.g. astemizole, terfenadine
  • cisapride (medicine used to treat digestive disorder)
This list does not include all medicines that may interact with Sodium stibogluconate.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on Sodium stibogluconate - Intralesional and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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