Premedication: Premedication should be selected at the discretion of the anaesthetist, taking into consideration the need of the individual patient.
Induction: Dosage should be individualised and titrate to the desired effect according to the patient's age and clinical status.
A short acting barbiturate or other intravenous induction agent may be administered followed by inhalation of sevoflurane.
Induction with sevoflurane may be achieved in oxygen or in combination with oxygen-nitrous oxide mixtures.
Alternatively, for Induction of anaesthesia in unpremedicated patients, inspired concentrations of up to 8% sevoflurane may be used.
Maintenance: Surgical levels of anaesthesia can usually be achieved with concentrations of 0.5 - 3% sevoflurane with or without the concomitant use of nitrous oxide.
Elderly: To maintain surgical anaesthesia in these patients, lesser concentrations of sevoflurane are normally required. See as follows for MAC values.
MAC (minimum alveolar concentration) values for sevoflurane decrease with age and with the addition of nitrous oxide.
The table as follows indicates average MAC values for different age groups: (See table).
Click on icon to see table/diagram/image
Emergence: Emergence times are generally short following sevoflurane anaesthesia. Therefore, patients may require early post-operative pain relief.