Somatostatin


Concise Prescribing Info
Indications/Uses
GI haemorrhage.
Dosage/Direction for Use
Adult : IV 250 mcg as a bolus inj, then infuse at 3.5 mcg/kg/hr until bleeding has ceased. May continue for a further 48-72 hr to prevent recurrent bleeding.
Dosage Details
Intravenous
Gastrointestinal haemorrhage
Adult: Initially, 250 mcg as a bolus inj over 3-5 min, followed by a continuous infusion of 3.5 mcg/kg/hr until bleeding has ceased. May continue for a further 48-72 hr to prevent recurrent bleeding.
Special Precautions
Monitor blood glucose levels. May inhibit intestinal absorption thus concomitant parenteral nutrition may be recommended.
Adverse Reactions
Rapid infusion may lead to abdominal discomfort, nausea, flushing, bradycardia.
Action
Description: Somatostatin is a polypetide obtained synthetically or from the hypothalamus. It acts by inhibiting the release of growth hormone from the anterior pituitary. It also inhibits the release of thyrotrophin and corticotropin from the pituitary, glucagon and insulin from the pancreas. It also regulates duodenal and gastric secretions. It may also play a role in pain perception.
Disclaimer: This information is independently developed by MIMS based on Somatostatin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
  • Somatostatin-Eumedica
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