Myopathy. Perform liver function tests prior to, 12 wk after initiation of therapy & semiannually thereafter. Asian patients. Not recommended in combination w/ gemfibrozil. Concomitant use w/ fibrates, niacin; drugs increasing plasma conc eg, certain PIs including combinations of ritonavir w/ atazanavir, lopinavir &/or tipanavir. Not to be used during pregnancy & lactation.