Strepsils Max Plus (Anaesthetic) Lozenge

Strepsils Max Plus (Anaesthetic) Lozenge

Manufacturer:

RB (Health)

Distributor:

Zuellig Pharma
Full Prescribing Info
Contents
Amylmetacresol, 2,4-dichlorobenzyl alcohol, lignocaine HCl.
Description
Each lozenge contains amylmetacresol 0.6 mg, 2,4-dichlorobenzyl alcohol 1.2 mg and lignocaine hydrochloride 10 mg.
Action
Pharmacology: Amylmetacresol and dybenal (2,4-dichlorobenzyl alcohol) have antiseptic properties. Lignocaine hydrochloride is a local anaesthetic of the amide type and has a fast onset and an intermediate duration of action.
Pharmacokinetics: Absorption: Lignocaine is readily absorbed from the gastrointestinal tract, from mucous membrane and through damaged skin.
Protein-Binding: Lignocaine is bound to plasma proteins, including α1-acid glycoprotein (AAG). The extent of binding is variable but is approximately 66%. Plasma protein-binding of lignocaine depends in part on the concentrations of both lignocaine and AAG.
Metabolism: Lignocaine is largely metabolised in the liver and first-pass metabolism is extensive and bioavailability is about 35% after oral administration. Approximately 90% of a given dose is dealkylated to form monoethylglycinexylidide (MEGX) and glycinexylidide (GX).
Excretion: Further metabolism occurs and metabolites are excreted in the urine with <10% of unchanged lignocaine. Lignocaine crosses the placenta and blood-brain barrier: It is excreted in the breast milk.
Indications/Uses
For symptomatic relief of mouth and throat infections including severe sore throat.
Dosage/Direction for Use
Adults and Children >12 years: 1 lozenge to be sucked every 2 hrs as required. No more than 8 lozenges to be sucked in any 24-hr period.
Overdosage
No overdosage situation have been encountered in humans.
Contraindications
Allergy or hypersensitivity to any of the ingredients of Strepsils Dual Action (Anaesthetic) Lozenge.
Special Precautions
Use in pregnancy & lactation: The safety of Strepsils Dual Action (Anaesthetic) Lozenge during pregnancy and lactation has not been established. It is not recommended for pregnant and nursing mothers unless the expected benefits to the mother outweigh the potential risk to the neonate.
Use in children: Strepsils Dual Action (Anaesthetic) Lozenge is not recommended for use in children <12 years.
Use In Pregnancy & Lactation
The safety of Strepsils Dual Action (Anaesthetic) Lozenge during pregnancy and lactation has not been established. It is not recommended for pregnant and nursing mothers unless the expected benefits to the mother outweigh the potential risk to the neonate.
Adverse Reactions
May occasionally cause allergic reactions. Taste perversion and burning sensation of the throat have been reported.
Storage
Store in a dry place, below 30°C.
Shelf-Life: 24 months.
ATC Classification
R02AA03 - dichlorobenzyl alcohol ; Belongs to the class of antiseptics used in throat preparations.
Presentation/Packing
Loz (pale blue-green, circular, with a characteristic flavour) 16's.
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