Increased adverse events w/ aspirin & other NSAIDs including ibuprofen & COX-2 selective inhibitors. Increased effects of anticoagulants, phenytoin. Reduced effects of antihypertensive, diuretics, mifepristone. Increased risk of GI bleeding w/ corticosteroids, antiplatelet agents & SSRIs. Increased plasma levels of cardiac glycosides, methotrexate, lithium. Increased risk of nephrotoxicity w/ ciclosporin, tacrolimus. Increased risk of hemotological toxicity w/ zidovudine. Increased risk of developing convulsions w/ quinolones. Altered blood glucose level w/ oral antidiabetics. Hyperkalaemia w/ K-sparing diuretics. Delayed excretion of flurbiprofen w/ probenecid, sulfinpyrazone.