Sulfathiazole


Concise Prescribing Info
Indications/Uses
Vaginal infections.
Dosage/Direction for Use
Adult : Vag Per g cream contains sulfathiazole 34.2 mg, sulphacetamide 28.6 mg, sulphabenzamide 37 mg and urea 6.4 mg: Apply 5 g twice daily for 4-6 days. Thereafter, reduce dosage to one-half or one-quarter.
Dosage Details
Vaginal
Vaginal infections
Adult: Cream (Sulphathiazole 34.2 mg/g, sulphacetamide 28.6 mg/g, sulphabenzamide 37 mg/g and urea 6.4 mg/g): 5g is applied intra-vaginally bid for 4 to 6 days. Thereafter the dosage may be reduced to one-half or one-quarter.
Contraindications
Sulphonamide sensitivity, kidney disease, glucose 6-phosphate deficiency (G6PD).
Action
Description: Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole. It is a short-acting sulfonamide, now rarely used systemically due to its toxicity.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Sulfathiazole from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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