Sulfathiazole: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Vaginal
Vaginal infections

Adult: Cream (Sulphathiazole 34.2 mg/g, sulphacetamide 28.6 mg/g, sulphabenzamide 37 mg/g and urea 6.4 mg/g): 5g is applied intra-vaginally bid for 4 to 6 days. Thereafter the dosage may be reduced to one-half or one-quarter.

Contraindications

Sulphonamide sensitivity, kidney disease, glucose 6-phosphate deficiency (G6PD).

Action

Description: Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole. It is a short-acting sulfonamide, now rarely used systemically due to its toxicity.

MIMS Class

Topical Antibiotics

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