SW Dexasone

SW Dexasone

dexamethasone

Manufacturer:

Sunward

Distributor:

Antah Pharma
Concise Prescribing Info
Contents
Dexamethasone
Indications/Uses
Primary or secondary adrenocortical insufficiency; endocrine, rheumatic, collagen, dermatologic, ophth, resp, hematologic, neoplastic & GI diseases, allergic & edematous states.
Dosage/Direction for Use
Tab Initially 0.75-9 mg daily depending on disease being treated. Less severe disease <0.75 mg daily. Severe disease >9 mg daily. Elixir 5-90 mL daily in divided doses.
Administration
Should be taken with food.
Contraindications
Hypersensitivity. Systemic fungal infections. Live vaccine administration.
Special Precautions
CHF, DM, HTN, recent intestinal anastomoses, infectious diseases, myasthenia gravis, ocular herpes simplex, quiescent TB; hyperthyroidism, hypothyroidism. May mask signs of infection. Avoid exposure to chicken pox or measles. Avoid abrupt w/drawal. Prolonged use. Chronic renal failure, cirrhosis. Women of childbearing potential. Pregnancy. Not to be used during lactation. Elderly.
Adverse Reactions
Fluid & electrolyte disturbances, muscle weakness, osteoporosis, acute pancreatitis, Cushingoid state, growth retardation, visual disturbances, increased IOP. Tab: Menstrual irregularities, latent DM manifestations, peptic ulcer w/ possible perforation & hemorrhage, impaired wound healing, convulsion, increased intracranial pressure w/ papilledema. Elixir: Amenorrhea, edema, HTN, mental disturbances, local atrophy, increased appetite.
Drug Interactions
Hypoprothrombinemia w/ aspirin. Decreased blood levels w/ phenytoin, phenobarb, ephedrine, rifampicin. Altered response of anticoagulants. Development of hypokalaemia w/ K-depleting diuretics. Increased risk of systemic effects w/ CYP3A inhibitors eg, cobicistat-containing products.
ATC Classification
H02AB02 - dexamethasone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
SW Dexasone elixir 0.5 mg/5 mL
Packing/Price
(pineapple flavour) 120 mL x 50 × 1's
Form
SW Dexasone tab 0.5 mg
Packing/Price
10 × 10 × 10's
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