Discontinue use if paradoxical bronchospasm occurs. Not to be initiated during exacerbation or in patients w/ significantly worsening or acutely deteriorating asthma. Active or quiescent pulmonary TB, fungal & viral airway infections. Cushing's syndrome, Cushingoid features, adrenal suppression, decreased bone mineral density, cataract, glaucoma, psychomotor hyperactivity, sleep disorders, anxiety, depression or aggression; periods of stress eg, severe infections, elective surgery; thyrotoxicosis, phaeochromocytoma, DM, untreated hypokalaemia, hypertrophic obstructive cardiomyopathy, idiopathic subvalvular aortic stenosis, severe HTN, aneurysm; severe CV disorders eg, ischaemic heart disease, tachyarrythmias or severe heart failure; QTc interval prolongation; visual disturbances. Pneumonia in patients w/ COPD. Risk of oropharyngeal candida infection. Monitor HPA axis function, K & blood glucose levels. Transferring patients from previous systemic steroid therapy. Avoid abrupt w/drawal. High-dose & prolonged use. Avoid concomitant treatment w/ itraconazole, ritonavir or potent CYP3A4 inhibitors. Concomitant use w/ xanthine derivative, steroids, diuretics. Pregnancy & lactation. Childn ≤11 yr or adolescents 12-17 yr w/ COPD; growth retardation in childn & adolescents.