Taurine


Concise Prescribing Info
Indications/Uses
Adjuvant therapy in CHF.
Dosage/Direction for Use
Adult : PO Dose used in clinical trials: 0.5-3 g/day.
Dosage Details
Oral
Adjuvant therapy in congestive heart failure
Adult: Dose used in clinical trials: 0.5-3 g daily.
Contraindications
Hypersensitivity.
Special Precautions
Renal failure.
Action
Description: Taurine, 2-aminoethane sulfonic acid, is a conditionally essential amino acid derived from methionine and cysteine metabolism. Unlike true amino acids, it is not incorporated into proteins and is one of the most abundant free amino acids found in various tissues e.g. retina, brain, skeletal and cardiac muscles. It is involved in bile acid conjugation as well as other physiological functions e.g. detoxification, membrane stabilisation, osmoregulation and cellular calcium levels modulation. Some of the clinical uses investigated include use in CHF, cystic fibrosis, toxic exposure and liver disorders. Human breast milk are found to be rich in taurine. It is widely found in infant formula and parenteral nutrition of low-birth-wt infants due to the low biosynthetic capacity of the human neonate to produce taurine.
Disclaimer: This information is independently developed by MIMS based on Taurine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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