Special Instructions for Use, Handling and Disposal: Instructions for dilution: Tecentriq should be prepared by a healthcare professional using aseptic technique. Use sterile needle and syringe to prepare Tecentriq. Withdraw the required volume of Tecentriq liquid concentrate from the vial and dilute to the required administration volume with 0.9% sodium chloride solution. Dilute with 0.9% Sodium Chloride Injection only. After dilution, the final concentration of the diluted solution should be between 3.2 and 16.8 mg/mL.
This medicinal product must not be mixed with other medicinal products.
No preservative is used in Tecentriq therefore each vial is for single use only. Discard any unused portion.
Incompatibilities: No incompatibilities have been observed between Tecentriq and IV bags with product-contacting surfaces of polyvinyl chloride (PVC), polyethylene (PE) or polypropylene (PP). In addition, no incompatibilities have been observed with in-line filter membranes composed of polyethersulfone or polysulfone, and infusion sets and other infusion aids composed of PVC, PE, polybutadiene, or polyetherurethane.
Disposal of unused/expired medicines: The release of pharmaceuticals in the environment should be minimized. Medicines should not be disposed of via wastewater and disposal through household waste should be avoided. Use established "collection systems", if available in the location.