Thioctic acid


Concise Prescribing Info
Indications/Uses
Diabetic neuropathy.
Dosage/Direction for Use
Adult : PO 600 mg/day.
Dosage Details
Oral
Diabetic neuropathy
Adult: 600 mg daily. May also be given via IV admin.
Administration
Should be taken on an empty stomach. Take 30 min before meals. Swallow whole, do not chew/crush.
Special Precautions
Pregnancy, lactation. Monitor blood glucose and adjust diabetic medication accordingly. May cause insulin autoimmune syndrome in diabetics.
Adverse Reactions
Allergic reactions such as skin rash, nausea, hypoglycemia.
Action
Description: Thioctic acid, or α-lipoic acid, is used for its antioxidant effects in the treatment of diabetic neuropathy. It has been tried in the treatment of liver dysfunction and in subacute necrotising encephalopathy. Thioctic acid and its reduced metabolite form a redox couple and may scavenge a wide range of reactive oxygen species.
Pharmacokinetics:
Distribution: Cross the blood brain barrier.
Disclaimer: This information is independently developed by MIMS based on Thioctic acid from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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