Adjunctive diagnostic tool for serum thyroglobulin (Tg) testing w/ or w/o radioiodine imaging in patients w/ well-differentiated thyroid cancer who have undergone thyroidectomy. Adjunctive treatment for radioiodine ablation of thyroid tissue remnants in patients who have undergone near-total or total thyroidectomy for well-differentiated thyroid cancer & who do not have evidence of distant metastatic thyroid cancer.
2 inj regimen: 0.9 mg IM to the buttock followed by 2nd 0.9 mg IM 24 hr later. Serum Tg testing Serum sample should be obtained 72 hr after final Thyrogen inj. Remnant ablation & diagnostic scanning Oral radioiodine: Given 24 hr after 2nd Thyrogen inj. Perform diagnostic scanning 48 hr after radioiodine administration.
View Thyrogen overdosage for action to be taken in the event of an overdose.
Special Precautions
Not to be inj IV. Thyrogen-induced hyperthyroidism. History of heart disease. Radiologically-confirmed & unconfirmed stroke in patients w/o known CNS metastases. Sudden, rapid & painful enlargement of residual thyroid tissue or distant metastases. Ensure adequate hydration. Renal impairment. Pregnancy & lactation. Ped. Elderly.