Adjunctive diagnostic tool for serum thyroglobulin (Tg) testing w/ or w/o radioiodine imaging in patients w/ well-differentiated thyroid cancer who have undergone thyroidectomy. Adjunctive treatment for radioiodine ablation of thyroid tissue remnants in patients who have undergone near-total or total thyroidectomy for well-differentiated thyroid cancer & who do not have evidence of distant metastatic thyroid cancer.
2 inj regimen: 0.9 mg IM to the buttock followed by 2nd 0.9 mg IM 24 hr later. Serum Tg testing Serum sample should be obtained 72 hr after final Thyrogen inj. Remnant ablation & diagnostic scanning Oral radioiodine: Given 24 hr after 2nd Thyrogen inj. Perform diagnostic scanning 48 hr after radioiodine administration.
Not to be inj IV. Thyrogen-induced hyperthyroidism. History of heart disease. Radiologically-confirmed & unconfirmed stroke in patients w/o known CNS metastases. Sudden, rapid & painful enlargement of residual thyroid tissue or distant metastases. Ensure adequate hydration. Renal impairment. Pregnancy & lactation. Ped. Elderly.