Tolperisone


Concise Prescribing Info
Indications/Uses
Spasticity and muscle spasms.
Dosage/Direction for Use
Adult : PO 50-150 mg 3 times/day.
Dosage Details
Oral
Muscle spasms, Spasticity
Adult: As hydrochloride: 50-150 mg tid.
Child: As hydrochloride: <6 yr: 5 mg/kg daily in 3 divided doses; 6-14 yr: 2-4 mg/kg daily in 3 divided doses.
Administration
Should be taken with food.
Contraindications
Myasthenia gravis.
Adverse Reactions
Muscular weakness, headache, hypotension, nausea, vomiting, abdominal discomfort.
Action
Description: Tolperisone is a centrally acting muscle relaxant.
Pharmacokinetics:
Absorption: Well absorbed from GI tract. Peak plasma concentration in 0.5-1 hr. Bioavailability: 20%.
Metabolism: Extensively metabolised by liver and kidney. Elimination half-life (IV): 1.5 hr.
Excretion: Excreted mainly via urine as metabolites.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Tolperisone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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