Tramadol - oral

Patient Medicine Information
Why do I need this medicine?
Tramadol is used to relieve moderate to severe pain.
How do I take this medicine?
Take Tramadol exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take Tramadol with or without food. Try to take it at the same time each day.

If you are taking the sustained-release tablet or capsule (usually labelled as "SR"), swallow it whole. Do not open, chew or crush the tablet or capsule.

If you are taking the orodispersible tablet:
  1. Remove it from the foil only just before you take it. Do not leave the orodispersible tablet exposed to air. Do not push the orodispersible tablet through the foil as it is fragile and easily broken.
  2. Remove the orodispersible tablet with dry hands by peeling the backing off the foil and tipping the tablet onto your dry hands.
  3. Place the orodispersible tablet directly on your tongue as soon as it is taken out of the foil. The orodispersible tablet will immediately start to melt on the tongue. It can then be swallowed with or without water.
Do not cut, break or crush the orodispersible tablets.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.
When should I not use this medicine?
Do not take Tramadol if you are currently taking or have taken a medicine that is used to treat depression known as a monoamine oxidase inhibitor (MAOI) in the last 14 days.
What should I take note of while taking this medicine?
Inform your doctor if you have any of the following:
  • liver disease
  • kidney disease
  • respiratory disease
  • depression
  • epilepsy (seizures or fits)
  • head injury or trauma
  • history of drug abuse
  • have consumed large amounts of alcohol or taken too many sleeping tablets, pain killers, other medicines that affect mood and emotions
Let your doctor know if you are pregnant or breastfeeding.

Individuals who are CYP2D6 ultra-rapid metabolisers may experience serious side effects from this medicine. Your doctor may perform genetic testing before giving you this medicine.
What side effects could I experience?
Tramadol may cause drowsiness and dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: flushing of the face, headache, dizziness with sensations of spinning, muscle weakness, tiredness, difficulty sleeping, constipation, nausea, dry mouth and rashes.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following
  • seizures (fits)
  • breathlessness or problems swallowing
  • swollen eyes or mouth
  • unusual behaviour or mood swings
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
DO NOT take Tramadol if you are currently taking or have taken a medicine that is used to treat depression known as a monoamine oxidase inhibitor (MAOI) such as isocarboxazid, phenelzine and tranylcypromine in the last 14 days.

Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines to treat epilepsy (seizures or fits) e.g. carbamazepine
  • medicines to treat HIV e.g. ritonavir, indinavir
  • medicines for fungal infection e.g. ketoconazole, voriconazole
  • blood-thinning medicine e.g. warfarin
  • certain antibiotics e.g. erythromycin, rifampicin
  • St. John’s wort (herbal medicine) 
This list does not include all medicines that may interact with Tramadol.

Always notify your doctor and pharmacist if you are taking any other medicines including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on tramadol - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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