Trileptal Overdosage





Full Prescribing Info
Isolated cases of overdose have been reported. The maximum dose taken was approximately 48,000 mg.
Signs and symptoms: Electrolyte and fluid balance conditions: hyponatraemia.
Eye disorders: diplopia, miosis, blurred vision.
Gastrointestinal disorders: nausea, vomiting, hyperkinesia.
General disorders and administration site conditions: fatigue.
Investigations: respiratory rate depression, QTc prolongation.
Nervous system disorders: drowsiness and somnolence, dizziness, ataxia, nystagmus, tremor, disturbances in coordination (coordination abnormal), convulsion, headache, coma, loss of consciousness, dyskinesia.
Psychiatric disorders: aggression, agitation, confusional state.
Vascular disorders: hypotension.
Respiratory, thoracic and mediastinal disorders: dyspnoea.
Management: There is no specific antidote. Symptomatic and supportive treatment should be administered as appropriate. Removal of the drug by gastric lavage and/or inactivation by administering activated charcoal should be considered.
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