Trivastal Retard 50

Trivastal Retard 50





Zuellig Pharma
Concise Prescribing Info
Parkinson's disease either as monotherapy or combined w/ dopatherapy from the outset or secondarily.
Dosage/Direction for Use
Monotherapy 3-5 tab daily in 3-5 divided doses, may be increased gradually by 1 tab every 3 days. Adjunct to dopatherapy 1-3 tab daily, may be increased gradually by 1 tab every 3 days.
Should be taken with food: Take at the end of a main meal. Swallow whole, do not chew/crush.
Hypersensitivity. CV shock; acute MI. Concomitant w/ antiemetic neuroleptics.
Special Precautions
Dyskinesia; postural orthostatic hypotension; abnormal behavior associated w/ confusion, agitation, aggression; somnolence & sudden sleep onset; risk of falls related to hypotension, sudden sleep onset or delirium; psychotic disorders; peripheral oedema; neuroleptic malignant syndrome. Regularly monitor onset of impulse control disorders eg, pathological/compulsive gambling, hypersexuality, increased libido, compulsive spending or shopping, excessive consumption of food, compulsive food disorders. Avoid abrupt discontinuation. Not to be used in patients w/ fructose intolerance, glucose & galactose malabsorption syndrome or sucrase-isomaltase deficiency. May affect ability to drive & use machines. Renal or hepatic failure. Not recommended in women of childbearing potential not using contraception. Not recommended during pregnancy & lactation. Childn <18 yr.
Adverse Reactions
Minor GI disorders eg, nausea, vomiting, flatulence; psychic disorders eg, confusion, hallucinations (visual, auditory, mixed), agitation; dizziness.
Drug Interactions
Reciprocal antagonism w/ antiemetic & antipsychotic neuroleptics (except clozapine), tetrabenazine. Increased sedative effect by alcohol. Increased central depression w/ other sedatives.
MIMS Class
Antiparkinsonian Drugs
ATC Classification
N04BC08 - piribedil ; Belongs to the class of dopamine agonists. Used in the management of Parkinson's disease.
Trivastal Retard 50 SR tab 50 mg
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