Unoprostone


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : Ophth Glaucoma; Ocular HTN As 0.12 or 0.15% soln: Instill 1 drop twice daily.
Dosage Details
Ophthalmic
Glaucoma, Ocular hypertension
Adult: Instil 1 drop of 0.12% or 0.15% solution into affected eye(s) bid.
Contraindications
Pregnancy; lactation.
Special Precautions
Monitor for eye colour change; risk factors for cystoid macular oedema. An interval of at least 5 min to be observed between different eyedrops. Contact lens to be re-inserted at least 15 min after application of unoprostone.
Adverse Reactions
Conjunctival hyperaemia, brown pigmentation particularly in those with mixed-color irides; ocular irritation and pain; darkening, thickening and lengthening of eyelashes; keratitis; corneal erosion and pain; discharge; burning; ocular itching; punctate epithelial keratopathy; headache; nasal congestion; dry mouth; tongue tip numbness; nausea; vomiting; palpitation; cystoid macular oedema; uveitis.
Action
Description: Unoprostone, a synthetic analogue of dinoprost (prostaglandin F), decreases intraocular pressure by increasing the uveoscleral outflow of aqueous humour.
Storage
Store below 8°C.
Disclaimer: This information is independently developed by MIMS based on Unoprostone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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