Uphalexin

Uphalexin

cefalexin

Manufacturer:

Duopharma Marketing

Distributor:

Duopharma Marketing
Concise Prescribing Info
Contents
Cefalexin
Indications/Uses
Resp tract, bone, GUT & dental infections; otitis media.
Dosage/Direction for Use
Adult 1-4 g daily in divided doses. Most infections 500 mg every 8 hr. Skin & soft tissue infections, streptococcal pharyngitis, mild & uncomplicated UTI 250 mg every 6 hr or 500 mg every 12 hr. Childn 25-50 mg/kg in divided doses. Skin & soft tissue infections, streptococcal pharyngitis, mild & uncomplicated UTI Dose to be administered every 12 hr. Most infections Childn ≥5 yr 250 mg every 8 hr. Severe infections Dosage may be doubled. Otitis media 75-100 mg/kg daily in 4 divided doses. β-haemolytic streptococcal infections At least 10 days.
Administration
May be taken with or without food: May be taken w/ meals to reduce GI discomfort.
Contraindications
Hypersensitivity to cefalexin & other cephalosporins.
Special Precautions
Penicillin sensitivity. Pseudomembranous colitis; overgrowth of non-susceptible organisms; superinfection. False +ve urinary glucose & Coombs’ test. Prolonged use. Renal impairment. Pregnancy & lactation. Cap: Previous hypersensitivity reactions to cephalosporins, carbapenems or other β-lactam agents.
Adverse Reactions
GI disturbances; hypersensitivity reactions including skin rashes, urticaria, eosinophilia, fever, reactions resembling serum sickness & anaphylaxis.
Drug Interactions
Decreased efficacy of estrogen-containing OCs. Reduced excretion w/ probenecid. Increased risk of renal damage w/ aminoglycosides eg, gentamicin. Enhanced nephrotoxicity w/ loop diuretics eg, frusemide.
MIMS Class
ATC Classification
J01DB01 - cefalexin ; Belongs to the class of first-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Uphalexin cap 500 mg
Packing/Price
5 × 10 × 10's
Form
Uphalexin granules for oral susp 125 mg/5 mL
Packing/Price
60 mL x 1's
Form
Uphalexin cap 250 mg
Packing/Price
10 × 10 × 10's
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