Vaccine, diphtheria toxoid


Concise Prescribing Info
Indications/Uses
For primary immunisation.
Dosage/Direction for Use
Adult : IM As a combination product w/ tetanus and inactivated poliomyelitis: 3 doses (0.5 mL each), at mthly intervals, booster dose of 0.5 mL after 5 yr, repeat 10 yr later.
Dosage Details
Intramuscular
Primary immunisation
Adult: As a combination product with tetanus and inactivated poliomyelitis: 3 doses of each 0.5 ml at intervals of 1 mth, booster dose of 0.5 ml after 5 yr, repeated 10 yr later.
Child: 2 mth-10 yr: As a combination product with tetanus, pertussis (acellular), inactivated poliomyelitis and adsorbed haemophilus type B conjugate: 3 doses of 0.5 ml at intervals of 1 mth. >10 yr: As a combination product with tetanus and inactivated poliomyelitis: 3 doses of each 0.5 ml at intervals of 1 mth, booster dose of 0.5 ml after 5 yr, repeated 10 yr later.
Contraindications
Hypersensitivity. Severe primary immunodeficiency. During or within 6 mth of stopping chemotherapy or radiotherapy treatment. Solid organ transplant and receiving immunosuppressants. Bone marrow transplant and within 12 mth of stopping immunosuppressive treatment. Patients receiving and within 3 mth of stopping high-dose systemic corticosteroids treatment. Immunosuppressed HIV positive patients.
Special Precautions
If alcohol or disinfectant is used for cleansing skin, ensure that it has evaporated before vaccination to prevent inactivation of live vaccines.
Adverse Reactions
Hypersensitivity. Induration, sterile abscess or local reaction, possibly with inflammation or lymphangitis at the inj site. Fever, headache and malaise.
Potentially Fatal: Anaphylaxis.
Drug Interactions
Live vaccines should normally be given at least 3 wk before or at least 3 mth after the use of immunoglobulin. Patients on immunosuppressants e.g. corticosteroids or antineoplastics may display reduced response to vaccines.
Action
Description: Diphtheria vaccines are used for active immunisation against diphtheria. The non-adsorbed vaccine has poor immunogenic properties and its effects are enhanced by admin as an adsorbed preparation. It is often used in combination with other vaccines e.g. tetanus toxoid.
Disclaimer: This information is independently developed by MIMS based on Vaccine, diphtheria toxoid from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in