Varilrix Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Live attenuated Oka strain of varicella-zoster virus not <10^3.3 plaque-forming units (PFU)

Indications/Uses

Active immunisation against varicella of healthy subjects from 12 mth onwards, susceptible high-risk patients & their susceptible healthy close contacts.

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Dosage/Direction for Use

SC Adult, adolescent ≥13 yr, childn 12 mth-12 yr, high-risk patient 2 doses w/ 2nd dose given at least 6 wk after 1st dose & not <4 wk.

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Overdosage

View Varilrix overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity to neomycin or after previous inj. Postpone vaccination in patients w/ acute severe febrile illness. Severe humoral or cellular immunodeficiency eg, patients w/ primary or acquired immunodeficiency states (total lymphocyte count <1,200/mm³); lack of cellular immune competence eg, leukaemia, lymphoma, blood dyscrasias, clinically manifest HIV infection; receiving immunosuppressants. Avoid pregnancy after 1 mth of vaccination.

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Special Precautions

Anaphylactic reaction. Not to be administered intravascularly or intradermally. Syncope. Immunocompromised patients. Allow alcohol & other disinfecting agents to evaporate from skin prior to inj. Women of childbearing potential. Not to be used during pregnancy. Lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Pain, redness. Rash; inj site swelling, fever (oral/axillary ≥37.5°C; rectal ≥38°C).

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Drug Interactions

Temporary depression of tuberculin skin sensitivity. Delay vaccination at least 3 mth in patients who have received immune globulins or blood transfusion. Reye's syndrome w/ salicylates. Short lived suppression of cell mediated immune response w/ measles vaccine. Not to be administered at the same time w/ other live attenuated vaccines.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Varilrix detailed prescribing information

Storage

View Varilrix storage conditions for details to ensure optimal shelf-life.

Description

View Varilrix description for details of the chemical structure and excipients (inactive components).

Action

View Varilrix mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Vaccines, Antisera & Immunologicals

ATC Classification

J07BK01 - varicella, live attenuated ; Belongs to the class of varicella viral vaccines.

Regulatory Classification

Presentation/Packing

Form

Varilrix vaccine 0.5 mL

Packing/Price

1's

Varilrix

vaccine, varicella-zoster

Manufacturer:

GlaxoSmithKline

Distributor:

Zuellig Pharma