Vaxcel Acyclovir IV Infusion 250 mg

Vaxcel Acyclovir IV Infusion 250 mg

aciclovir

Manufacturer:

Kotra Pharma

Distributor:

Kotra Pharma
Concise Prescribing Info
Contents
Acyclovir Na
Indications/Uses
Herpes simplex & varicella zoster infections. Herpes simplex infection prophylaxis in immunocompromised patients. Herpes simplex infections in neonate.
Dosage/Direction for Use
Adult Herpes simplex, varicella zoster infections & herpes simplex prophylaxis in immunocompromised patient 5 mg/kg every 8 hr. Herpes encephalitis, varicella zoster infections in immunocompromised patient & herpes simplex infection in neonate 10 mg/kg every 8 hr. Childn 3 mth-12 yr Herpes simplex, varicella zoster infections 250 mg/m2 every 8 hr. Varicella zoster infection in immunocompromised childn, herpes encephalitis 500 mg/m2 every 8 hr. CrCl 25-50 mL/min 5 or 10 mg/kg every 12 hr, 10-25 mL/min 5 or 10 mg/kg every 24 hr, 0-10 mL/min 5 or 10 mg/kg or 500 mg/m2 should be halved & administered every 24 hr & after dialysis.
Contraindications
Hypersensitivity to acyclovir or valacyclovir.
Special Precautions
Renal impairment. Pregnancy & lactation. Elderly.
Adverse Reactions
Phlebitis; nausea, vomiting; reversible increased liver enzymes; pruritus, urticaria, rashes including photosensitivity; increased blood urea & creatinine.
Drug Interactions
Increased AUC by probenecid & cimetidine; mycophenolate mofetil. Monitor changes in renal function w/ cyclosporine, tacrolimus.
MIMS Class
ATC Classification
J05AB01 - aciclovir ; Belongs to the class of nucleosides and nucleotides excluding reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.
Presentation/Packing
Form
Vaxcel Acyclovir IV Infusion 250 mg powd for inj 250 mg
Packing/Price
10 × 1's
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