Vaxcel Acyclovir IV Infusion 250 mg

Vaxcel Acyclovir IV Infusion 250 mg



Kotra Pharma


Kotra Pharma
Concise Prescribing Info
Acyclovir Na
Herpes simplex & varicella zoster infections. Herpes simplex infection prophylaxis in immunocompromised patients. Herpes simplex infections in neonate.
Dosage/Direction for Use
Adult Herpes simplex, varicella zoster infections & herpes simplex prophylaxis in immunocompromised patient 5 mg/kg every 8 hr. Herpes encephalitis, varicella zoster infections in immunocompromised patient & herpes simplex infection in neonate 10 mg/kg every 8 hr. Childn 3 mth-12 yr Herpes simplex, varicella zoster infections 250 mg/m2 every 8 hr. Varicella zoster infection in immunocompromised childn, herpes encephalitis 500 mg/m2 every 8 hr. CrCl 25-50 mL/min 5 or 10 mg/kg every 12 hr, 10-25 mL/min 5 or 10 mg/kg every 24 hr, 0-10 mL/min 5 or 10 mg/kg or 500 mg/m2 should be halved & administered every 24 hr & after dialysis.
Hypersensitivity to acyclovir or valacyclovir.
Special Precautions
Renal impairment. Pregnancy & lactation. Elderly.
Adverse Reactions
Phlebitis; nausea, vomiting; reversible increased liver enzymes; pruritus, urticaria, rashes including photosensitivity; increased blood urea & creatinine.
Drug Interactions
Increased AUC by probenecid & cimetidine; mycophenolate mofetil. Monitor renal function changes w/ cyclosporine, tacrolimus.
MIMS Class
ATC Classification
J05AB01 - aciclovir ; Belongs to the class of nucleosides and nucleotides excluding reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.
Vaxcel Acyclovir IV Infusion 250 mg powd for inj 250 mg
10 × 1's
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