2-4 g daily in 1:1 ratio in equally divided doses 12 hrly. Severe or refractory infections
May be increased up to 8 g of the 1:1 ratio. Patient may require additional cefoperazone administered separately. Administer 12 hrly in equally divided doses. Sulbactam max daily dose: 4 g. Childn
40-80 mg/kg daily in 1:1 ratio 6-12 hrly in equally divided doses. Serious or refractory infections
May be increased up to 160 mg/kg daily in 2-4 equally divided doses. Neonate in 1st wk of life
Given 12 hrly, max: 80 mg/kg daily of sulbactam dose. Intermittent infusion
1 g/20 mL administered for >15-60 min. IV inj
1 g/20 mL administered for at least 3 min.